GPR173

Entrez Summary: This gene encodes a member of the G-protein coupled receptor 1 family. This protein contains 7 transmembrane domains and conserved cysteine residues. [provided by RefSeq, Nov 2009].
UniProt Summary: Orphan receptor.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Rapamycin 2μM plus Cyclosporin-A 3μM R07 exp307	-2.26
Fas-L 44ng/ml R08 exp482	-2.16
HMS-I2 1μM R06 exp286	-1.95
NN-Diethyl-meta-toluamide 100μM R05 exp237	2.01

Global Fraction of Cell Lines Where Essential: 0/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/26
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution

gonadotropin-releasing hormone receptor activity
cellular response to gonadotropin-releasing hormone
response to gonadotropin-releasing hormone
negative regulation of neuron migration
regulation of neuron migration
negative regulation of cell migration
cellular response to peptide hormone stimulus
negative regulation of cell motility
negative regulation of neurogenesis
negative regulation of cellular component movement
negative regulation of nervous system development
negative regulation of locomotion
cellular response to peptide
negative regulation of cell development
response to peptide hormone
response to peptide
cellular response to organonitrogen compound
cellular response to hormone stimulus
cellular response to nitrogen compound
negative regulation of cell differentiation
G protein-coupled receptor activity
regulation of neurogenesis
regulation of cell migration
response to hormone
regulation of cell motility
regulation of nervous system development
regulation of cell development
negative regulation of developmental process
regulation of locomotion
regulation of cellular component movement
response to organonitrogen compound
cellular response to oxygen-containing compound
response to nitrogen compound
negative regulation of multicellular organismal process
cellular response to endogenous stimulus
G protein-coupled receptor signaling pathway
response to endogenous stimulus
generation of neurons
response to oxygen-containing compound
neurogenesis