GRIK1

Gene Information
  • Official Symbol: GRIK1
  • Official Name: glutamate ionotropic receptor kainate type subunit 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 2897
  • UniProt: P39086
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 11800
  • Expression level (log2 read counts): -1.85

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1