HBZ

Entrez Summary: N/A
UniProt Summary: The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

haptoglobin binding
organic acid binding
haptoglobin-hemoglobin complex
hemoglobin complex
oxygen carrier activity
erythrocyte maturation
oxygen transport
gas transport
hydrogen peroxide catabolic process
oxygen binding
erythrocyte development
peroxidase activity
hydrogen peroxide metabolic process
antibiotic catabolic process
myeloid cell development
cofactor catabolic process
erythrocyte differentiation
erythrocyte homeostasis
cellular oxidant detoxification
cellular detoxification
antibiotic metabolic process
myeloid cell homeostasis
reactive oxygen species metabolic process
detoxification
iron ion binding
anatomical structure maturation
heme binding
drug catabolic process
drug transport
cell maturation
homeostasis of number of cells
cellular response to toxic substance
myeloid cell differentiation
developmental maturation
cofactor metabolic process
drug metabolic process
response to toxic substance
hemopoiesis
hematopoietic or lymphoid organ development
immune system development