IL17B

Entrez Summary: N/A
UniProt Summary: Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of cytokine production involved in inflammatory response
regulation of cytokine production involved in inflammatory response
positive regulation of inflammatory response
cytokine activity
regulation of inflammatory response
positive regulation of cytokine production
positive regulation of defense response
inflammatory response
positive regulation of response to external stimulus
regulation of cytokine production
regulation of defense response
regulation of response to external stimulus
cell-cell signaling
defense response
regulation of response to stress
extracellular space
positive regulation of multicellular organismal process
immune response