LRRCC1

Gene Information
  • Official Symbol: LRRCC1
  • Official Name: leucine rich repeat and coiled-coil centrosomal protein 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 85444
  • UniProt: Q9C099
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a centrosomal protein that maintains the structural integrity of the centrosome and plays a key role in mitotic spindle formation. The encoded protein contains an N-terminal leucine-rich repeat domain and a C-terminal coiled-coil domain. It associates with the centrosome throughout the cell cycle and accumulates on the mitotic centrosome. [provided by RefSeq, Mar 2017].
  • UniProt Summary: Required for the organization of the mitotic spindle. Maintains the structural integrity of centrosomes during mitosis. {ECO:0000269|PubMed:18728398}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 17467
  • Expression level (log2 read counts): 5.18

Expression Distribution

  • Last modified: 2025/12/10 20:19
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