LY6G6F

Entrez Summary: N/A
UniProt Summary: May play a role in the downstream signal transduction pathways involving GRB2 and GRB7. {ECO:0000269|PubMed:12852788}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Fluvastatin 2.2μM R06 exp282	-1.93
Rapamycin 2μM plus Cyclosporin-A 3μM R07 exp307	-1.74
Calcium Ionophore 0.4μM R07 exp342	-1.73
Tozasertib 0.1μM R07 exp414	2.06

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

platelet alpha granule membrane
platelet degranulation
regulated exocytosis
exocytosis
secretion by cell
export from cell
secretion
vesicle-mediated transport