MFAP2

Entrez Summary: Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
UniProt Summary: Component of the elastin-associated microfibrils.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	1/22
urinary tract	0/29
uterus	0/5

Expression Distribution

post-embryonic eye morphogenesis
post-embryonic animal organ morphogenesis
microfibril
post-embryonic animal morphogenesis
post-embryonic animal organ development
embryonic eye morphogenesis
post-embryonic development
positive regulation of cold-induced thermogenesis
extracellular matrix structural constituent
regulation of cold-induced thermogenesis
eye morphogenesis
sensory organ morphogenesis
embryonic organ morphogenesis
extracellular matrix organization
eye development
visual system development
collagen-containing extracellular matrix
sensory system development
extracellular structure organization
embryonic organ development
sensory organ development
embryonic morphogenesis
animal organ morphogenesis
embryo development
positive regulation of multicellular organismal process
extracellular region