MGAT4B

• Official Symbol: MGAT4B
• Official Name: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
• Aliases and Previous Symbols: N/A
• Entrez ID: 11282
• UniProt: Q9UQ53
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: N/A
• UniProt Summary: Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N- glycan biosynthesis.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 15789
• Expression level (log2 read counts): 4.77

Expression Distribution

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MGAT4B Expression in NALM6 Cells: 4.77