MMEL1

Gene Information
  • Official Symbol: MMEL1
  • Official Name: membrane metalloendopeptidase like 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 79258
  • UniProt: Q495T6
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity). {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 3699
  • Expression level (log2 read counts): -0.06

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1