MRPL10

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 375/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	14/28
blood	16/28
bone	10/26
breast	22/33
central nervous system	19/56
cervix	4/4
colorectal	10/17
esophagus	10/13
fibroblast	0/1
gastric	8/16
kidney	7/21
liver	13/20
lung	41/75
lymphocyte	5/16
ovary	8/26
pancreas	10/24
peripheral nervous system	7/16
plasma cell	3/15
prostate	0/1
skin	12/24
soft tissue	4/9
thyroid	0/2
upper aerodigestive	12/22
urinary tract	19/29
uterus	1/5

Expression Distribution

Gene	Correlation
COA3	0.413
VARS2	0.412

large ribosomal subunit
mitochondrial large ribosomal subunit
mitochondrial translational elongation
mitochondrial translational termination
translational termination
mitochondrial translation
translational elongation
cellular protein complex disassembly
mitochondrial gene expression
ribonucleoprotein complex
structural constituent of ribosome
protein-containing complex disassembly
ribosome biogenesis
translation
mitochondrial inner membrane
cellular component disassembly
peptide biosynthetic process
ribonucleoprotein complex biogenesis
amide biosynthetic process
peptide metabolic process
cellular amide metabolic process
mitochondrion
RNA binding
organonitrogen compound biosynthetic process
cellular nitrogen compound biosynthetic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
protein-containing complex subunit organization
gene expression