MYH6

• Official Symbol: MYH6
• Official Name: myosin heavy chain 6
• Aliases and Previous Symbols: N/A
• Entrez ID: 4624
• UniProt: P13533
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3. [provided by RefSeq, Feb 2017].
• UniProt Summary: Muscle contraction.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 5621
• Expression level (log2 read counts): -4.01

Expression Distribution

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MYH6 Expression in NALM6 Cells: -4.01