MYO1D

Entrez Summary: N/A
UniProt Summary: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Myosin TH1
Myosin head

early endosome to recycling endosome transport
actin-dependent ATPase activity
axolemma
apical dendrite
microfilament motor activity
vesicle-mediated transport between endosomal compartments
smooth endoplasmic reticulum
plasma membrane raft
myelin sheath
myosin complex
brush border
calcium-dependent protein binding
negative regulation of phosphatase activity
negative regulation of dephosphorylation
perikaryon
cell cortex
cytosolic transport
regulation of phosphatase activity
basolateral plasma membrane
calmodulin binding
actin filament binding
regulation of dephosphorylation
protein domain specific binding
cytoplasmic vesicle
early endosome
endosome
axon
neuron projection
neuronal cell body
forebrain development
negative regulation of hydrolase activity
negative regulation of phosphate metabolic process
negative regulation of phosphorus metabolic process
brain development
head development
negative regulation of catalytic activity
central nervous system development
negative regulation of molecular function
regulation of hydrolase activity
ATP binding