NAP1L1

Entrez Summary: N/A
UniProt Summary: May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Parthenolide 2.5μM R05 exp238	-2.22
Erlotinib 10μM R05 exp216	-2.18
4-Nitroquinoline-1-oxide 0.5μM R08 exp446	-1.81
Rapamycin 1μM R00 exp29	1.71
Nifuroxazide 5μM R03 exp102	1.75
GSK461364A 0.1μM R03 exp126	1.76
Golgicide-A 4μM R03 exp122	1.83

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of neural precursor cell proliferation
regulation of neural precursor cell proliferation
melanosome
nucleosome assembly
chromatin assembly
chromatin assembly or disassembly
nucleosome organization
DNA packaging
protein-DNA complex assembly
DNA replication
protein-DNA complex subunit organization
DNA conformation change
positive regulation of neurogenesis
positive regulation of nervous system development
positive regulation of cell development
chromatin organization
regulation of neurogenesis
cellular protein-containing complex assembly
positive regulation of cell population proliferation
regulation of nervous system development
regulation of cell development
positive regulation of cell differentiation
chromosome organization
positive regulation of developmental process
RNA binding
generation of neurons
protein-containing complex assembly
regulation of cell population proliferation
neurogenesis
cellular macromolecule biosynthetic process
positive regulation of multicellular organismal process
macromolecule biosynthetic process
regulation of cell differentiation
protein-containing complex subunit organization
membrane