NCAM1

Entrez Summary: This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Expression Distribution

regulation of semaphorin-plexin signaling pathway
commissural neuron axon guidance
interferon-gamma-mediated signaling pathway
virus receptor activity
viral entry into host cell
anchored component of membrane
entry into host cell
entry into host
interaction with host
cellular response to interferon-gamma
response to interferon-gamma
viral life cycle
axon guidance
neuron projection guidance
collagen-containing extracellular matrix
axonogenesis
MAPK cascade
signal transduction by protein phosphorylation
external side of plasma membrane
axon development
cell morphogenesis involved in neuron differentiation
neuron projection morphogenesis
plasma membrane bounded cell projection morphogenesis
cell projection morphogenesis
cell part morphogenesis
chemotaxis
taxis
cell morphogenesis involved in differentiation
cell surface
Golgi membrane
neuron projection development
cytokine-mediated signaling pathway
viral process
cell morphogenesis
innate immune response
symbiotic process
neuron development
interspecies interaction between organisms
cellular component morphogenesis
cell adhesion