NLGN4X

• Official Symbol: NLGN4X
• Official Name: neuroligin 4 X-linked
• Aliases and Previous Symbols: N/A
• Entrez ID: 57502
• UniProt: Q8N0W4
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].
• UniProt Summary: Putative neuronal cell surface protein involved in cell- cell-interactions.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 15313
• Expression level (log2 read counts): -1.07

Expression Distribution

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NLGN4X Expression in NALM6 Cells: -1.07