OMG

Entrez Summary: N/A
UniProt Summary: Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

LRR 4
LRRNT

neuron projection regeneration
negative regulation of axonogenesis
negative regulation of cell morphogenesis involved in differentiation
anchored component of membrane
negative regulation of neuron projection development
regeneration
negative regulation of cell projection organization
regulation of axonogenesis
negative regulation of neuron differentiation
negative regulation of neurogenesis
regulation of cell morphogenesis involved in differentiation
negative regulation of nervous system development
negative regulation of cell development
regulation of cell morphogenesis
regulation of neuron projection development
regulation of neuron differentiation
neuron projection development
regulation of plasma membrane bounded cell projection organization
negative regulation of cellular component organization
regulation of cell projection organization
negative regulation of cell differentiation
neuron development
regulation of neurogenesis
regulation of nervous system development
cell adhesion
regulation of cell development
biological adhesion
negative regulation of developmental process
neuron differentiation
regulation of anatomical structure morphogenesis
plasma membrane bounded cell projection organization
cell projection organization
negative regulation of multicellular organismal process
generation of neurons
neurogenesis
cell development
cellular response to stress
regulation of cell differentiation