OTOGL

Entrez Summary: The protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2012].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Expression Distribution

Screen	Score
35°C R06 exp302	-1.92
ETC-159 50μM R08 exp480	1.86

alpha-L-arabinofuranosidase activity
L-arabinose metabolic process
arabinose metabolic process
pentose metabolic process
sensory perception of sound
sensory perception of mechanical stimulus
monosaccharide metabolic process
carbohydrate metabolic process
sensory perception
nervous system process
small molecule metabolic process
extracellular region
system process