PAFAH1B3

Official Symbol: PAFAH1B3
Official Name: platelet activating factor acetylhydrolase 1b catalytic subunit 3
Aliases and Previous Symbols: N/A
Entrez ID: 5050
UniProt: Q15102
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: N/A
UniProt Summary: Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

platelet-activating factor acetyltransferase activity
1-alkyl-2-acetylglycerophosphocholine esterase activity
lipid catabolic process
protein heterodimerization activity
spermatogenesis
male gamete generation
gamete generation
brain development
head development
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
central nervous system development
multi-organism reproductive process
identical protein binding
lipid metabolic process
reproductive process
reproduction
organic substance catabolic process
membrane