PHACTR1

Gene Information
  • Official Symbol: PHACTR1
  • Official Name: phosphatase and actin regulator 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 221692
  • UniProt: Q9C0D0
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Plays a role in cell motility. Plays a role in the formation of tubules by endothelial cells. Regulates PPP1CA activity. Required for normal cell survival. {ECO:0000269|PubMed:21798305, ECO:0000269|PubMed:21939755}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 11305
  • Expression level (log2 read counts): 7.18

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1