PJA2

Gene Information
  • Official Symbol: PJA2
  • Official Name: praja ring finger ubiquitin ligase 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 9867
  • UniProt: O43164
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes. {ECO:0000269|PubMed:12036302, ECO:0000269|PubMed:21423175}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 13877
  • Expression level (log2 read counts): 6.27

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1