PSAPL1

Entrez Summary: N/A
UniProt Summary: May activate the lysosomal degradation of sphingolipids. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

prostate gland growth
epithelial cell differentiation involved in prostate gland development
prostate gland development
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
organ growth
sphingolipid metabolic process
membrane lipid metabolic process
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
lysosome
urogenital system development
developmental growth
growth
regulation of lipid metabolic process
gland development
reproductive structure development
reproductive system development
developmental process involved in reproduction
epithelial cell differentiation
cellular lipid metabolic process
epithelium development
lipid metabolic process
G protein-coupled receptor signaling pathway
reproductive process
reproduction
extracellular space
tissue development