PTGFRN

Entrez Summary: N/A
UniProt Summary: Inhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

myoblast fusion involved in skeletal muscle regeneration
myotube differentiation involved in skeletal muscle regeneration
lipid droplet organization
myoblast fusion
skeletal muscle tissue regeneration
syncytium formation by plasma membrane fusion
cell-cell fusion
syncytium formation
myotube differentiation
tissue regeneration
regeneration
striated muscle cell differentiation
muscle cell differentiation
developmental growth
growth
muscle structure development
wound healing
response to wounding
cell surface
anatomical structure formation involved in morphogenesis
endoplasmic reticulum membrane
Golgi apparatus
tissue development