PTPN4

Entrez Summary: N/A
UniProt Summary: May act at junctions between the membrane and the cytoskeleton.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Chloramphenicol 2μM R00 exp12	1.72
Demecolcine 0.03μM R05 exp228	1.83

non-membrane spanning protein tyrosine phosphatase activity
cytoplasmic side of plasma membrane
cytoskeletal protein binding
peptidyl-tyrosine dephosphorylation
protein dephosphorylation
dephosphorylation
cytoskeleton
cellular response to cytokine stimulus
response to cytokine