RALGAPA2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
SGC0649 7μM R03 exp150	-2.35
Mubritinib 0.2μM R01 exp48	-1.87
UM131593 0.2μM R03 exp106	-1.84
Rotenone 2μM R00 exp33	-1.75
NN-Diethyl-meta-toluamide 500μM R08 exp438	1.9

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

activation of GTPase activity
GTPase activator activity
regulation of small GTPase mediated signal transduction
positive regulation of GTPase activity
regulation of GTPase activity
protein heterodimerization activity
positive regulation of hydrolase activity
regulation of hydrolase activity
positive regulation of catalytic activity
extracellular space
positive regulation of molecular function
regulation of intracellular signal transduction