RASGRF1

Entrez Summary: N/A
UniProt Summary: Promotes the exchange of Ras-bound GDP by GTP. {ECO:0000269|PubMed:11389730}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glutamate receptor binding
regulation of Rac protein signal transduction
Ras guanyl-nucleotide exchange factor activity
long-term memory
regulation of NMDA receptor activity
regulation of neuronal synaptic plasticity
positive regulation of Ras protein signal transduction
regulation of glutamate receptor signaling pathway
Rho guanyl-nucleotide exchange factor activity
positive regulation of small GTPase mediated signal transduction
regulation of neurotransmitter receptor activity
activation of GTPase activity
guanyl-nucleotide exchange factor activity
memory
growth cone
regulation of Rho protein signal transduction
regulation of cation channel activity
regulation of signaling receptor activity
regulation of synaptic plasticity
regulation of Ras protein signal transduction
response to endoplasmic reticulum stress
regulation of ion transmembrane transporter activity
learning or memory
regulation of transmembrane transporter activity
regulation of transporter activity
cognition
small GTPase mediated signal transduction
neuron projection
regulation of cation transmembrane transport
regulation of small GTPase mediated signal transduction
MAPK cascade
signal transduction by protein phosphorylation
positive regulation of GTPase activity
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
regulation of ion transmembrane transport
regulation of GTPase activity
cell population proliferation
regulation of transmembrane transport
behavior