RASL10A

Entrez Summary: N/A
UniProt Summary: Potent inhibitor of cellular proliferation. {ECO:0000269|PubMed:15833841}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
NN-Dimethylsphingosine 2.5μM R08 exp508	-2.14
Hinokiflavone 12μM R08 exp487	-1.94
CI-1040 9.5μM R08 exp472	-1.73
Rotenone 20μM R00 exp34	1.7
GSK461364A 0.1μM R03 exp126	1.95
SB203580 25μM R03 exp149	1.96
Quinacrine 2.5μM R03 exp146	1.99

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Ras
Miro

small GTPase mediated signal transduction
GTPase activity
GTP binding
nucleolus
intracellular signal transduction