RHNO1

Gene Information
  • Official Symbol: RHNO1
  • Official Name: RAD9-HUS1-RAD1 interacting nuclear orphan 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 83695
  • UniProt: Q9BSD3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation (IR) during the S phase. Recruited to sites of DNA damage through interaction with the 9-1-1 cell-cycle checkpoint response complex and TOPBP1 in a ATR-dependent manner. Required for the progression of the G1 to S phase transition. Plays a role in the stimulation of CHEK1 phosphorylation. {ECO:0000269|PubMed:21659603}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 3092
  • Expression level (log2 read counts): 4.46

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1