SEC22C

Entrez Summary: N/A
UniProt Summary: May be involved in vesicle transport between the ER and the Golgi complex. {ECO:0000269|PubMed:9501016}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Lead acetate 2000μM R08 exp497	-2.05
MLN-4924 2μM R00 exp22	-1.81
6-Thio-2-deoxyguanosine 2μM R06 exp259	-1.73
LLY-283 2.6μM R06 exp290	1.77
∆-9-Tetrahydrocannabinol 30μM R08 exp445	1.82

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

endoplasmic reticulum to Golgi vesicle-mediated transport
Golgi vesicle transport
endoplasmic reticulum membrane
endoplasmic reticulum
protein transport
intracellular transport
peptide transport
amide transport
establishment of protein localization
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport