SLC28A3
Gene Information
- Official Symbol: SLC28A3
- Official Name: solute carrier family 28 member 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 64078
- UniProt: Q9HAS3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2:1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin and 3-deazauridine. {ECO:0000269|PubMed:11032837, ECO:0000269|PubMed:16446384, ECO:0000269|PubMed:17140564}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 12908
- Expression level (log2 read counts): -2.79