SNX12

Entrez Summary: N/A
UniProt Summary: May be involved in several stages of intracellular trafficking. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/26
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution

Screen	Score
1-Methyl-nicotinamide-chloride 1000μM R03 exp113	-1.77
Wortmannin 5μM R00 exp38	1.94

negative regulation of early endosome to late endosome transport
negative regulation of cytoplasmic transport
regulation of early endosome to late endosome transport
regulation of cytoplasmic transport
negative regulation of protein maturation
negative regulation of protein processing
negative regulation of intracellular transport
regulation of protein processing
regulation of protein maturation
phosphatidylinositol binding
negative regulation of protein catabolic process
negative regulation of protein transport
negative regulation of establishment of protein localization
regulation of endocytosis
early endosome
negative regulation of catabolic process
enzyme binding
regulation of intracellular transport
negative regulation of proteolysis
regulation of protein catabolic process
negative regulation of transport
regulation of vesicle-mediated transport
regulation of protein transport
regulation of proteolysis
regulation of peptide transport
regulation of establishment of protein localization
regulation of cellular localization
regulation of catabolic process
regulation of protein localization
negative regulation of cellular protein metabolic process
negative regulation of protein metabolic process
protein transport
peptide transport
amide transport
establishment of protein localization
negative regulation of gene expression
nitrogen compound transport
regulation of transport
membrane