SSR4
Gene Information
- Official Symbol: SSR4
- Official Name: signal sequence receptor subunit 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 6748
- UniProt: P51571
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011].
- UniProt Summary: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 11415
- Expression level (log2 read counts): 5.93
SSR4 Expression in NALM6 Cells: 5.93
