SSTR3

Entrez Summary: N/A
UniProt Summary: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. {ECO:0000269|PubMed:1337145}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

somatostatin receptor activity
somatostatin signaling pathway
hormone-mediated apoptotic signaling pathway
somatostatin receptor signaling pathway
neuropeptide binding
non-motile cilium
cellular response to estradiol stimulus
peptide binding
ciliary membrane
cellular response to glucocorticoid stimulus
cellular response to corticosteroid stimulus
cerebellum development
neuropeptide signaling pathway
metencephalon development
response to estradiol
response to glucocorticoid
hindbrain development
response to corticosteroid
hormone-mediated signaling pathway
cellular response to steroid hormone stimulus
response to starvation
cilium
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
apoptotic signaling pathway
response to steroid hormone
signaling receptor binding
forebrain development
response to nutrient levels
cellular response to lipid
response to extracellular stimulus
cellular response to organic cyclic compound
spermatogenesis
male gamete generation
cellular response to hormone stimulus
negative regulation of cell population proliferation
gamete generation
G protein-coupled receptor activity
brain development
head development
multicellular organismal reproductive process