STK32B

Entrez Summary: This gene encodes a serine-threonine protein kinase. Serine-threonine kinases transfer phosphate molecules to the oxygen atoms of serine and threonine. A genomic deletion affecting this gene has been associated with Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
All-trans-Retinoic-Acid 8μM R07 exp333	-1.84
Cytochalasin-B 5μM R07 exp349	-1.83
Geldanamycin 0.01μM R05 exp235	-1.74
Rotenone 2μM R00 exp33	-1.72
Dorsomorphin 5μM R07 exp357	1.73
RO-3306 3 to 4μM on day4 R04 exp165	1.76
A-366 10μM R03 exp115	1.83

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Pkinase Tyr
Pkinase

peptidyl-serine phosphorylation
peptidyl-serine modification
protein serine/threonine kinase activity
peptidyl-amino acid modification
protein phosphorylation
phosphorylation
ATP binding
intracellular signal transduction