SURF4

Entrez Summary: N/A
UniProt Summary: May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi. {ECO:0000269|PubMed:18287528}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

early endosome to Golgi transport
protein exit from endoplasmic reticulum
azurophil granule membrane
endoplasmic reticulum-Golgi intermediate compartment membrane
endoplasmic reticulum-Golgi intermediate compartment
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
transport vesicle
retrograde transport, endosome to Golgi
Golgi organization
cytosolic transport
endosomal transport
Golgi vesicle transport
endomembrane system organization
neutrophil degranulation
neutrophil activation involved in immune response
neutrophil mediated immunity
neutrophil activation
granulocyte activation
leukocyte degranulation
myeloid leukocyte mediated immunity
myeloid cell activation involved in immune response
myeloid leukocyte activation
Golgi membrane
positive regulation of organelle organization
leukocyte activation involved in immune response
cell activation involved in immune response
regulated exocytosis
leukocyte mediated immunity
exocytosis
leukocyte activation
endoplasmic reticulum membrane
intracellular protein transport
secretion by cell
export from cell
cell activation
immune effector process
secretion
positive regulation of cellular component organization
regulation of organelle organization
protein transport