THBS3
Gene Information
- Official Symbol: THBS3
- Official Name: thrombospondin 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 7059
- UniProt: P49746
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011].
- UniProt Summary: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 3291
- Expression level (log2 read counts): 2.89