TMCO3

Gene Information
  • Official Symbol: TMCO3
  • Official Name: transmembrane and coiled-coil domains 3
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 55002
  • UniProt: Q6UWJ1
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: N/A
Function Summary
  • Entrez Summary: This gene encodes a member of the monovalent cation:proton antiporter 2 (CPA2) family of transporter proteins. Members of this family typically couple the export of monovalent cations, such as potassium or sodium, to the import of protons across cellular membranes. Mutations in this gene have been identified in patients with a rare inherited vision defect, cornea guttata with anterior polar cataract. [provided by RefSeq, Mar 2017].
  • UniProt Summary: Probable Na(+)/H(+) antiporter. {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 6162
  • Expression level (log2 read counts): 4.87

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1