TMEM150C

Entrez Summary: N/A
UniProt Summary: Component of a mechanosensitive cation channel. Confers mechanically activated (MA) currents with slow inactivation kinetics. May contribute to proprioception. {ECO:0000250|UniProtKB:Q8C8S3}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
MKC9989 10μM R03 exp133	-1.88
Hydroxyurea 100μM R07 exp329	-1.75

proprioception
mechanosensitive ion channel activity
neuromuscular process controlling posture
cellular response to mechanical stimulus
neuromuscular process
response to mechanical stimulus
lysosome
lysosomal membrane
cellular response to abiotic stimulus
cellular response to environmental stimulus
regulation of autophagy
cellular response to external stimulus
regulation of cellular catabolic process
sensory perception
regulation of catabolic process
response to abiotic stimulus
transmembrane transport
nervous system process
integral component of plasma membrane
system process