UST

Entrez Summary: N/A
UniProt Summary: Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Gal-3-0 sulfotr
Sulfotransfer 2

protein sulfation
dermatan sulfate biosynthetic process
dermatan sulfate metabolic process
dermatan sulfate proteoglycan biosynthetic process
sulfation
dermatan sulfate proteoglycan metabolic process
sulfotransferase activity
proteoglycan biosynthetic process
proteoglycan metabolic process
glycosaminoglycan biosynthetic process
mucopolysaccharide metabolic process
aminoglycan biosynthetic process
establishment of cell polarity
glycosaminoglycan metabolic process
aminoglycan metabolic process
sulfur compound biosynthetic process
regulation of axonogenesis
monocarboxylic acid biosynthetic process
establishment or maintenance of cell polarity
carboxylic acid biosynthetic process
organic acid biosynthetic process
regulation of cell morphogenesis involved in differentiation
glycoprotein biosynthetic process
sulfur compound metabolic process
glycoprotein metabolic process
regulation of cell morphogenesis
regulation of neuron projection development
drug metabolic process
monocarboxylic acid metabolic process
small molecule biosynthetic process
Golgi membrane
carbohydrate derivative biosynthetic process
regulation of neuron differentiation
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
regulation of neurogenesis
carboxylic acid metabolic process
regulation of nervous system development
regulation of cell development
oxoacid metabolic process