VARS

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 677/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	25/28
blood	25/28
bone	22/26
breast	27/33
central nervous system	52/56
cervix	4/4
colorectal	17/17
esophagus	12/13
fibroblast	1/1
gastric	16/16
kidney	20/21
liver	20/20
lung	70/75
lymphocyte	16/16
ovary	26/26
pancreas	23/24
peripheral nervous system	12/16
plasma cell	14/15
prostate	0/1
skin	22/24
soft tissue	8/9
thyroid	2/2
upper aerodigestive	19/22
urinary tract	28/29
uterus	5/5

Expression Distribution

valyl-tRNA aminoacylation
valine-tRNA ligase activity
aminoacyl-tRNA metabolism involved in translational fidelity
aminoacyl-tRNA editing activity
regulation of translational fidelity
tRNA aminoacylation for protein translation
tRNA aminoacylation
amino acid activation
tRNA metabolic process
cellular amino acid metabolic process
translation
peptide biosynthetic process
ncRNA metabolic process
amide biosynthetic process
peptide metabolic process
cellular amide metabolic process
carboxylic acid metabolic process
oxoacid metabolic process
organic acid metabolic process
organonitrogen compound biosynthetic process
ATP binding
cellular nitrogen compound biosynthetic process
RNA metabolic process
cellular macromolecule biosynthetic process
small molecule metabolic process
macromolecule biosynthetic process
gene expression