VGF

Entrez Summary: N/A
UniProt Summary: May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system. {ECO:0000250}. Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity against P. Pastoris. {ECO:0000269|PubMed:23250050}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

response to dietary excess
neuropeptide hormone activity
insulin secretion
response to cold
ovarian follicle development
peptide hormone secretion
hormone secretion
hormone transport
female gonad development
transport vesicle
development of primary female sexual characteristics
response to cAMP
female sex differentiation
response to organophosphorus
response to purine-containing compound
protein secretion
establishment of protein localization to extracellular region
growth factor activity
protein localization to extracellular region
signal release
peptide secretion
response to temperature stimulus
glucose homeostasis
carbohydrate homeostasis
gonad development
development of primary sexual characteristics
response to insulin
cytoplasmic vesicle
sex differentiation
endoplasmic reticulum lumen
defense response to bacterium
post-translational protein modification
response to peptide hormone
generation of precursor metabolites and energy
reproductive structure development
reproductive system development
response to peptide
response to nutrient levels
response to extracellular stimulus
regulation of hormone levels