ZDHHC15

Entrez Summary: The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
UniProt Summary: Palmitoyltransferase specific for GAP43 and DLG4/PSD95. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/26
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution

synaptic vesicle maturation
palmitoyltransferase activity
peptidyl-L-cysteine S-palmitoylation
peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
protein-cysteine S-palmitoyltransferase activity
protein palmitoylation
peptidyl-cysteine modification
protein lipidation
lipoprotein biosynthetic process
lipoprotein metabolic process
protein targeting to membrane
protein acylation
developmental maturation
establishment of protein localization to membrane
vesicle organization
protein targeting
protein localization to membrane
Golgi membrane
peptidyl-amino acid modification
Golgi apparatus
intracellular protein transport
endoplasmic reticulum
organonitrogen compound biosynthetic process
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
establishment of localization in cell
nitrogen compound transport