ZDHHC3

Gene Information
  • Official Symbol: ZDHHC3
  • Official Name: zinc finger DHHC-type palmitoyltransferase 3
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 51304
  • UniProt: Q9NYG2
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Palmitoyltransferase with broad specificity (PubMed:21926431, PubMed:23034182). Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability (By similarity). Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. May also palmitoylate DLG4, DNAJC5 and SNAP25 (By similarity). {ECO:0000250|UniProtKB:Q8R173, ECO:0000269|PubMed:21926431, ECO:0000269|PubMed:23034182}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 11025
  • Expression level (log2 read counts): 5.61

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1