ZNF570

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Doxycycline 10μM R00 exp18	-2.72
Hippuristanol 0.12μM R08 exp489 no dilution day6	-1.81
D-Fructose 10000μM R06 exp279	-1.71
DKK1 89ng/ml R08 exp477	-1.71
MK-1775 0.32μM R02 exp75	-1.71
BI-6727 0.04μM R03 exp98	1.73
LY2090314 0.003μM R08 exp499	1.84
LY2090314 0.003μM R08 exp500 no dilution day6	1.95

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

KRAB
zf-C2H2

DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific