ABCA8

Entrez Summary: N/A
UniProt Summary: ATP-dependent lipophilic drug transporter. {ECO:0000269|PubMed:12379217}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
DABN 20μM R00 exp17	-1.78
UM0130462 0.025 to 0.035μM day4 R05 exp247	1.91

ABC2 membrane 3
ABC tran

lipid transporter activity
ATPase-coupled transmembrane transporter activity
ATPase activity
lipid transport
lipid localization
intracellular membrane-bounded organelle
ion transmembrane transport
transmembrane transport
ion transport
ATP binding