ADAT2

Entrez Summary: N/A
UniProt Summary: Probably participates in deamination of adenosine-34 to inosine in many tRNAs. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 94/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	5/28
blood	1/28
bone	4/26
breast	3/33
central nervous system	11/56
cervix	1/4
colorectal	0/17
esophagus	1/13
fibroblast	0/1
gastric	2/16
kidney	4/21
liver	4/20
lung	9/75
lymphocyte	1/16
ovary	2/26
pancreas	3/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	4/24
soft tissue	0/9
thyroid	1/2
upper aerodigestive	4/22
urinary tract	9/29
uterus	0/5

Expression Distribution

tRNA wobble adenosine to inosine editing
tRNA-specific adenosine-34 deaminase complex
tRNA-specific adenosine-34 deaminase activity
adenosine to inosine editing
base conversion or substitution editing
tRNA wobble base modification
tRNA modification
tRNA processing
RNA modification
tRNA metabolic process
ncRNA processing
ncRNA metabolic process
zinc ion binding
RNA processing
RNA metabolic process
gene expression