AJAP1

Entrez Summary: N/A
UniProt Summary: Plays a role in cell adhesion and cell migration. {ECO:0000269|PubMed:16410724, ECO:0000269|PubMed:17267690}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Ethanol 0.01 R05 exp234	1.72
Geldanamycin 0.015 to 0.025μM on day4 R07 exp316	2.21

regulation of polarized epithelial cell differentiation
spanning component of plasma membrane
cell-cell contact zone
negative regulation of cell-matrix adhesion
cytoplasmic side of plasma membrane
negative regulation of cell-substrate adhesion
negative regulation of wound healing
beta-catenin binding
negative regulation of response to wounding
cell-cell adherens junction
regulation of cell-matrix adhesion
regulation of wound healing
regulation of epithelial cell differentiation
regulation of response to wounding
regulation of morphogenesis of an epithelium
basolateral plasma membrane
regulation of cell-substrate adhesion
regulation of animal organ morphogenesis
protein-containing complex binding
negative regulation of cell adhesion
apical plasma membrane
negative regulation of response to external stimulus
cell surface
regulation of cell adhesion
cell adhesion
biological adhesion
regulation of anatomical structure morphogenesis
regulation of response to external stimulus
regulation of response to stress
negative regulation of response to stimulus
regulation of cell differentiation