AKNA

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

neuroblast delamination
neuroblast division in subventricular zone
delamination
forebrain neuroblast division
neuroblast division
neuronal stem cell division
somatic stem cell division
cell proliferation in forebrain
neuroblast proliferation
stem cell division
stem cell proliferation
forebrain generation of neurons
epithelial to mesenchymal transition
neural precursor cell proliferation
fibrillar center
centriole
mesenchymal cell differentiation
negative regulation of cell-cell adhesion
mesenchyme development
negative regulation of cell adhesion
microtubule
regulation of inflammatory response
forebrain development
regulation of cell-cell adhesion
DNA-binding transcription activator activity, RNA polymerase II-specific
centrosome
cell division
RNA polymerase II proximal promoter sequence-specific DNA binding
cell population proliferation
regulation of cell adhesion
intracellular membrane-bounded organelle
brain development
regulation of defense response
head development
central nervous system development
regulation of response to external stimulus
positive regulation of transcription by RNA polymerase II
regulation of response to stress
generation of neurons
positive regulation of transcription, DNA-templated