ALPK3

Entrez Summary: N/A
UniProt Summary: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation. Plays a role in cardiomyocyte differentiation (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

I-set
Alpha kinase

cardiac muscle cell development
cardiac cell development
cardiac muscle cell differentiation
cardiocyte differentiation
striated muscle cell development
muscle cell development
cardiac muscle tissue development
striated muscle cell differentiation
muscle cell differentiation
striated muscle tissue development
muscle tissue development
protein serine/threonine kinase activity
muscle structure development
heart development
circulatory system development
protein phosphorylation
phosphorylation
ATP binding
cell development
tissue development