ANXA8L1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Cannabidiol 13μM R08 exp465	1.86
Parthenolide 2.5μM R05 exp238	1.96

negative regulation of phospholipase A2 activity
negative regulation of serine-type endopeptidase activity
negative regulation of serine-type peptidase activity
negative regulation of phospholipase activity
regulation of serine-type peptidase activity
regulation of serine-type endopeptidase activity
regulation of phospholipase A2 activity
negative regulation of lipase activity
calcium-dependent phospholipid binding
regulation of phospholipase activity
endosome organization
cell
regulation of lipase activity
endosomal transport
negative regulation of endopeptidase activity
negative regulation of peptidase activity
vesicle organization
negative regulation of proteolysis
regulation of endopeptidase activity
endomembrane system organization
regulation of peptidase activity
negative regulation of hydrolase activity
calcium ion binding
regulation of proteolysis
negative regulation of catalytic activity
negative regulation of cellular protein metabolic process
negative regulation of protein metabolic process
negative regulation of molecular function
regulation of hydrolase activity
intracellular transport
establishment of localization in cell
vesicle-mediated transport