BAIAP2L2

Entrez Summary: The protein encoded by this gene binds phosphoinositides and promotes the formation of planar or curved membrane structures. The encoded protein is found in RAB13-positive vesicles and at intercellular contacts with the plasma membrane. [provided by RefSeq, Dec 2012].
UniProt Summary: Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

clathrin complex
actin crosslink formation
positive regulation of actin cytoskeleton reorganization
cell-cell contact zone
vesicle membrane
regulation of actin cytoskeleton reorganization
actin filament bundle assembly
actin filament bundle organization
positive regulation of actin filament polymerization
plasma membrane organization
phospholipid binding
positive regulation of protein polymerization
cytoplasmic vesicle membrane
regulation of actin filament polymerization
regulation of actin polymerization or depolymerization
regulation of actin filament length
positive regulation of supramolecular fiber organization
actin cytoskeleton
positive regulation of cytoskeleton organization
regulation of protein polymerization
actin filament organization
positive regulation of protein complex assembly
regulation of actin filament organization
regulation of actin cytoskeleton organization
regulation of supramolecular fiber organization
regulation of cellular component size
regulation of actin filament-based process
endomembrane system organization
regulation of protein complex assembly
supramolecular fiber organization
actin cytoskeleton organization
regulation of anatomical structure size
positive regulation of cellular component biogenesis
regulation of cytoskeleton organization
actin filament-based process
positive regulation of organelle organization
membrane organization
regulation of cellular component biogenesis
cytoskeleton organization
positive regulation of cellular component organization